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Featured article of the month archive - 2021
Welcome to the CannaQAwiki 2021 archive for the Featured Article of the Month.
Featured article of the month: March 2021:
"Methods for quantification of cannabinoids: A narrative review"
Around 144 cannabinoids have been identified in the Cannabis plant; among them tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most prominent ones. Because of the legal restrictions on cannabis in many countries, it is difficult to obtain standards to use in research; nonetheless, it is important to develop a cannabinoid quantification technique, with practical pharmaceutical applications for quality control of future therapeutic cannabinoids. To find relevant articles for this narrative review paper, a combination of keywords such as "medicinal cannabis," "analytical," "quantification," and "cannabinoids" were searched for in PubMed, EMBASE, MEDLINE, Google Scholar, and Cochrane Library (Wiley) databases. (Full article...)
Featured article of the month: February 2021:
"Analysis of phenolic compounds in commercial Cannabis sativa L. inflorescences using UHPLC-Q-Orbitrap HRMS"
Industrial hemp (Cannabis sativa L., family Cannabaceae) contains a vast number of relevant bioactive organic compounds, namely polyphenols, including flavonoids, phenolic acids, phenol amides, and lignanamides, which are well known for their therapeutic properties. Nowadays, many polyphenol-containing products made from herbal extracts are marketed, claiming to have health-promoting effects. In this context, industrial hemp inflorescences may represent an innovative source of bioactive compounds to be used in nutraceutical formulations. The aim of this work was to provide a comprehensive analysis of the polyphenolic fraction contained in polar extracts of four different commercial cultivars—Kompolti, Tiborszallasi, Antal, and Selected Carmagnola (CS)—of hemp inflorescence ... (Full article...)
Featured article of the month: January 2021:
"Analysis of cannabidiol, delta-9-tetrahydrocannabinol, and their acids in CBD/hemp oil products"
Hemp products are readily available and are aggressively marketed for their health and medicinal benefits. Most consumers of these products are interested because of their cannabidiol (CBD) content, which has taken the natural products industry by storm. The CBD and delta-9-tetrahydrocannabinol (delta-9-THC) concentrations in these products are often absent, and even where labeled, the accuracy of the label amounts is often questionable. In order to gain a better understanding of the CBD content, fifty hemp products were analyzed by gas chromatography coupled with mass spectrometry (GC-MS) for CBD, delta-9-THC, tetrahydrocannabinolic acid (delta-9-THCAA), and cannabidiolic acid (CBDA). Delta-9-THCAA and CBDA are the natural precursors of delta-9-THC and CBD in the plant material. (Full article...)