RefWork:Past, Present, and Future of Cannabis Laboratory Testing and Regulation in the United States/Future of cannabis regulation, testing, and market trends
What good would be a guide to the rapidly changing cannabis testing and regulation climate without some analysis of what the future may hold? This fourth chapter looks at the future of cannabis regulation and the associated market, as well as the future of lab testing and production. It also touches on fears of "Big Marijuana" and examines non-U.S. policy and how it may affect U.S. regulation in the future.
5. Future of cannabis regulation, testing, and market trends
5.1 Regulation, market, and research
Until effective and demonstrable policy change takes place in the U.S. federal government concerning marijuana, the country's researchers, doctors, patients, laboratory personnel, and entrepreneurs will have to keep fighting uncertainty and a convoluted patchwork of state and federal regulations. More certain is mounting evidence that a growing majority of U.S. voters believe the federal government should not be enforcing its laws in states where cannabis is legal: 64 percent agreed on this in 2012, rising to 71 percent in 2017. As for legal marijuana in general, a record high 68 percent of Americans believed it should be legal at the national level in November 2021. Despite such support, it remains up to interest groups and the states to twist the arm of the federal government. Legal representatives at Thompson Coburn expressed this idea well in a blog post in November 2016:
The cannabis industry may have to consider forcing the federal hand by providing credible data on the safety of cannabis as it was invited to do in the DEA decision, in addition to the continuing to support the groundswell of approval at the state level. At some point, in the near future, the state regulatory position and the federal position will have to be reconciled. The industry can and should prompt that reconciliation by a clear united message to federal lawmakers. Without that, it remains unlikely that agencies, such as the FDA, will change its position on cannabis. A lack of change will inhibit market growth and prevent the cannabis industry from reaching its potential.
The obvious issue of expanding research and testing on cannabis and addressing its safety is acquiring the product within a legal framework and a reasonable time frame. As mentioned previously, the DEA has recognized the need for more federally approved growers than the NIDA center at the University of Mississippi (which came under fire in March 2017 for not testing its provided samples for mold and other contaminants in any standardized fashion), and in 2016 they began accepting applications for additional entities looking to grow marijuana for researchers.
In January 2020, the topic of needing more legitimate cannabis sources for cannabis research was brought up yet again, this time in the context of an official hearing exclusively on cannabis by the House Health Subcommittee of the House Committee on Energy and Commerce, titled "Cannabis Policies for the New Decade." The hearing provided an opportunity for legislators to discuss the "catch-22" of regulation and medical research: "Research is restricted because cannabis is currently considered a Schedule 1 drug under the Controlled Substance Act, yet more research would better determine if marijuana should be rescheduled or descheduled." Lawmakers and witnesses both agreed that another limiter was having the University of Mississippi as the sole DEA-approved supplier of research-quality cannabis.
Ever slow to act, the U.S. government's Drug Enforcement Agency (DEA) finally, on December 18, 2020, finalized its amended "21 Code of Federal Regulations 1318 to facilitate the cultivation of marihuana for research purpose and other licit purposes to ensure compliance with the Controlled Substances Act (CSA) and treaty obligations." This added an additional five grow-ops to support researchers.
Optimistically, this will mean researchers will have more options for acquiring research-quality cannabis in the future. This should in turn allow researchers a shot at more focused studies that provide efficacy and safety data related to the medical use of cannabis. In fact, this has been a goal of Dr. Susan Weiss, Division Director of Extramural Research at the National Institute on Drug Abuse (NIDA) for some time. In July 2016 testimony to the U.S. Judiciary Committee and in an April 2017 research paper published in The International Journal of Drug Policy, Weiss cautiously recognized and promoted the need for further evidence-based cannabis research, emphasizing both the healthy and detrimental effects evident so far in the plant and its constituents:
Multiple agencies (NIH, ONDCP, DEA, and FDA) are working together to find ways to streamline the process to facilitate research while meeting international and legislative obligations under the Single Convention on Narcotic Drugs and the Controlled Substances Act. In addition to actions taken by the Department of Health and Humans Services to eliminate the Public Health Services (PHS) committee review for non-federally funded marijuana research, the DEA recently streamlined the administrative process for CBD research to allow researchers to obtain a waiver of the requirement for review of changes to an approved protocol in their DEA research registrations, and is attempting to address the marijuana diversity and product development concern by licensing additional manufacturers.
Other entities have put subtle pressure on the federal government to better recognize and accommodate the need for further research. In January 2017, the National Academies of Sciences, Engineering, and Medicine published a massive cannabis literature review. This 440-page report detailed the National Academies' findings after reviewing more than 10,700 abstracts related to cannabis. Among its final recommendations, the authors called for:
- public and private entities to fund and support a national cannabis research initiative that looks to fill key knowledge gaps;
- government agencies to develop research methods and standards that may act as a guide towards higher-quality cannabis research;
- government agencies, non-profit associations, and state and local health departments to fund and support efforts to improve federal, state, and local public health surveillance systems and efforts; and
- government, non-government, and industry entities to work together towards developing a report on existing regulatory barriers to research and how to overcome them.
As of August 2022, it's unclear what effects this report has had. Regarding the first recommendation of a national cannabis research initiative, no such entity has fully taken up the charge. The National Institute of Drug Abuse (NIDA) has arguably filled these shoes the most, having since produced numerous reports and re-emphasized its role as both an intermediary supplier of cannabis for researchers and a major funder of research on the misuse and negative effects of cannabis. However, as Daniel Mallinson, a cannabis policy researcher at Pennsylvania State University, notes in August 2020, the funding and reporting of NIDA, as a government entity, is a reflection of the government's budget, and thus "is a political statement about what we value as a society," adding that "the fact that most of the cannabis money is going to drug abuse and probably to cannabis use disorder versus medical purposes ... says something." A national cannabis research initiative that focuses more on therapeutic qualities than strictly the detrimental would be more welcome.
Regarding the rest of the recommendations, some progress has been made. As discussed in the second chapter, progress continues to be made on formal testing and accreditation standards for cannabis testing labs. However, this progress has been made almost exclusively by those outside the federal government. If government agencies were to rubber-stamp such standard methods and accreditation processes, it would arguably lend more weight to those methods and processes. Some states like Colorado continue to fund public health research and surveillance data collection, and in October 2020, the American Public Health Association (APHA) published a policy statement calling for "an evidence-based public health approach to regulating and controlling the legal commerce of cannabis products." However, a more concerted effort by other states' health departments would potentially have a greater impact. Finally, the call for a multi-pronged "report on existing regulatory barriers to research" and how to overcome those barriers has yet to be heeded. Numerous articles have been published in journals in recent years, but it will likely take a larger think-tank of groups to make a more impactful proposal to legalization holdouts.
While the growing discussion on enabling research is encouraging, some researchers such as Mayo Clinic psychiatrist and researcher Michael Bostwick have historically been less convinced that the barriers will fall—claiming federal entities shift too much focus on the detrimental effects and not enough on the potential benefits—and aren't optimistic about the direction the government will take. Despite this pessimism, predictions—and reports—of substantial revenues in states where recreational marijuana is legalized or could be legalized persist. A 2017 estimate by market research and analytics company New Frontier Data put the U.S. marijuana industry at $24 billion by 2025, and a 2022 study by Grand View Research put it at $40 billion by 2030. Yet entities such as the Denver-based Marijuana Policy Group and cannabis law firm Vicente Sederberg LLC have in the past preached caution when dealing with tax revenue estimates and economic projections in the U.S. cannabis market, pointing to CIBC World Markets' grossly inflated tax revenue estimate of $142 CAD ($106 USD) per resident in January 2016, an overshot of about 300 percent. "This is a fast-paced, changing market with varying different dynamics that have more to do based on governmental and regulatory dynamics than they do on consumer dynamics," said Vicente Sederberg's director of economics and research Andrew Livingston.
Indeed, current and future regulatory dynamics seem to be the biggest wildcards in making market-based predictions, with predicted tax and associated revenue estimates capable of both being significantly too high (by inadequately taking into account local and regional cultural and economic statuses) or too low (by not anticipating new states legalization efforts, research breakthroughs, or ties to other mainstream but related industries). Additionally, too much regulation can put a stranglehold on a state's cannabis program development—as it has done in Minnesota—causing related grow-ops and laboratories to take significant losses or even go out of business.
Finally, on a social level, the push by many to legalize marijuana and, by extension, push for beneficial changes in federal marijuana policy, has been driven even further by dramatic increase in use of and health consequences surrounding opioids in the United States.  What's not clear is how effective a replacement cannabis would be. Dr. Weiss again provides context, this time in the February 2018 workshop Cannabis and the opioid crisis: A multidisciplinary review:
I think we need to be very circumspect in what we are expecting from cannabis with respect to the opioid epidemic. There is no doubt that there are many patients suffering from pain, and we do not have a lot of options to treat it, especially chronic pain. Moreover, the cannabinoid system has a lot of promise regarding analgesic potential and alternative medication approaches. Whether it is the plant, components of the plant, or other strategies to modify endocannabinoid function—these are all possibilities that we need to explore to both help abate the opioid crisis and treat patients with pain who continue to suffer.
From that same workshop, several additional insights were revealed:
- The National Academies' 2017 research recognizes "the classification of cannabis as a Schedule I substance [as something] that impedes the advancement of cannabis and cannabinoid research." Getting past that will require the federal government living up to its 2016 promise to expand approved grow-ops.
- Getting marijuana rescheduled is further challenged by the fact that an entire plant and its constituents are scheduled. Difficulties arise because when we talk about rescheduling marijuana, the question has to be asked: "Are you talking about a plant that is mostly THC, that is mostly CBD (cannabidiol), that has unspecified different components in it?"
- A major question remains concerning "whether cannabinoids and opioids interact at a pharmacological level." To further study this, not only do well organized studies need to be designed, but also, as previously mentioned, access to quality samples and a willingness to see the benefit in such research is still required.
As of August 2022, the Marijuana Data Collection Act is still making its way through the legal quagmire, stuck in the Senate's Committee on Health, Education, Labor, and Pensions. Citing many of the previously mentioned issues and more, the proposed bill asks for the National Academy of Sciences "to conduct and update biennially a study on the effects of State legalized marijuana programs," among other tasks. Specifically the research would look at revenue impacts, medicinal use and safety, correlation with opioid abuse, criminal justice impacts, and employment impacts.> Whether or not this bill passes, one may argue that its intent is inline with the sentiment of representatives at Thompson Coburn: "forcing the federal hand by providing credible data on the safety of cannabis."
5.2 Lab testing
A January 2021 report by Global Market Insights (GMI) found the U.S. cannabis testing market to be valued at about $2 billion in 2020, with a compound annual growth rate (CAGR) of 10.4 percent through 2027. At a global level, GMI's October 2021 report found the total market value to be somewhere around $3 billion in 2020, with a CAGR of 21.1 percent through 2027, affected positively by medical application growth, growth in research institution investment, and cultivator and laboratory growth, negatively by a lack of uniform regulations and testing standards. A more conservative number was offered by Coherent Market Insights in July 2022, indicating a global market valued at $1.66 billion in 2022, potentially growing to $4.5 billion by 2030.
As for advances in cannabis lab testing, Kuzdzal et al. of Shimadzu envision a future where improvements in standardization, quality control, and research will shift what is tested and how it's tested:
The cannabis industry and cannabis testing are in their infancies. As the need for better quality control continues and standardization is introduced, it is likely that lower limits for the various cannabis contaminants will be established and regulations will be introduced. Mass spectrometry will likely play a greater role in quantitation as detection levels are lowered and confirmatory tests are required. The health benefits of terpenes present in cannabis will also provide a fertile area of scientific research. CBD, CBG and other compounds appear to have a synergistic relationship with each other as well as with various THC forms and terpenes. This field needs much more investigation to determine mechanisms of action, bioavailability and health benefits.
Lab testing of cannabis should continue to provide more exact and useful results as methods and standards continue to evolve. Disparity of results between two labs for the same sample are continuing to narrow as states increasingly add testing requirements to their cannabis legislature. Those testing requirements are increasingly based off a growing body of recommendations, guidance, and standards developed by the likes of the Americans for Safe Access Foundation (ASAF), American Herbal Pharmacopoeia (AHP), American Herbal Products Association (AHPA), Association of Official Agricultural Chemists (AOAC), American Oil Chemists' Society (AOCS), and the Association of Public Health Laboratories. Already, the groundwork for standard methods is being created by the AOAC and ASTM International, which continue to work on standardizing the determination and quantitation of cannabinoid concentrations, residual solvents, and pesticide amounts. Proficiency tests such as the Emerald Test, which allows multiple labs to test an anonymous sample and compare results, should also continue to drive improved performance from cannabis testing labs.
Finally, the role automation can play in cannabis testing labs is increasingly being discussed. This includes the implementation of environmental data loggers, direct-capture balances, sample preparation automation, and inventory tracking tools. Of course, software tools like the laboratory information management system (LIMS) also play a role in smoothing out workflows and reducing errors. However, automation solutions may move from something that is casually worth investing in to something that is critical to maintaining competitive strength, particularly if the U.S. government makes cannabis legal at the federal level. As more competitors enter the market, having automation to ensure quality and performance could be vital to labs who may have been around early on without automation.
Another potential trend to keep an eye on with these testing laboratories: consolidation. Currently there's not a lot of data on the extent consolidation has affected the number of cannabis testing labs or how they operate; the industry is arguably still in its infancy. Regardless, mentions in press and practical examples demonstrate that consolidation is a real concern for the industry, if not now in the future. Suggestion of such came from Steep Hill Halent's CEO David Lampach in late 2013, anticipating "huge consolidation in general and fewer companies as a result." GreenWave Advisors, CannaSafe Analytics, and Kramer Holcomb Sheik have also lent their voices to this idea.
In the fall of 2019, some discussion of California's laboratory testing market suggested consolidation could still occur. However, at the time a majority of the state's labs were not anywhere close to full capacity, a potential indicator of California's market not reaching fully saturated potential. Additionally, the likelihood of new labs opening up will be low due to the lack of saturation. This doesn't necessarily preclude lab consolidation, but it may be possible that labs with buying power could still consider purchasing other labs in order to gain a bigger piece of the pie. In some cases—where it's actually legal—licensed producers are acquiring laboratories. In Canada, for example, several producers have acquired licensed cannabis testing and research laboratories to bring them in-house, citing greater flexibility and more security for proprietary testing and research. Even in the U.S., consolidation among not just labs but also growers and distributors is not uncommon and may continue as the industry further continues to evolve.
Outside the lab, on the production side, resides a glimpse of technology that ties several of the previously mentioned ideas together: growing cannabis as an environmentally modified organism (EMO). A June 2016 article published in Motherboard referenced the Controlled Environment Systems Research Facility (CESRF) in Canada and its effort to apply innovations in growing plants in closed environments (such as on spaceships) to cannabis production. Specifically, the researchers see promise in being able to precisely control grow conditions to produce a plant with a particular ratio of active chemicals. As such, the previously mentioned synergistic relationship of cannabis' chemicals can be more carefully studied, and the end product, once studied and methodically tested, could potentially "achieve the status of a conventional pharmaceutical commodity that a doctor can rely on and prescribe." CESRF isn't alone in developing grow technology that can tailor the necessary conditions for a particular strain. Over the years, Israeli-linked start-ups (see the last section "Non-U.S. policy" for more) like Corsica Innovations (LEAF), Flux Farm (Eddy), and Eroll Grow Tech (Seedo) have developed similar grow technology that may transform future research. And Front Range Biosciences continues with its Clean Stock program, which "uses tissue culture to help clean up, store, mass-produce and certify plants, ensuring they are disease-free and true to type."
With better research, more definitive fact-based decisions can be made in the regulatory sphere, better guiding medical and recreational marijuana policy. That said, keep an eye on developments in controllable production methods; advances in this area stand to improve many of the other facets of research and testing discussed.
As production facilities (as well as testing laboratories) become more prominent throughout the U.S., another concern is beginning to emerge in the cannabis market: workplace safety. An August 2018 report by Chemistry World brought up several chemical accidents at cultivation facilities in Arizona that raised eyebrows in chemical safety groups. A commercial greenhouse cleaner at one cannabis facility ended with 16 employees being treated, and another involving "improperly stored hazardous materials" caused significant property damage. Safety groups and researchers remain concerned that as the cannabis industry rapidly expands, safety concerns may not get taken seriously by operators. As for workers themselves, a Colorado State University study says they may be taking safety more seriously, but nearly 50 percent of them complain of not receiving adequate training on "biological, chemical and physical hazards" inherent to their work. In addition to training, grow-ops, laboratories, and governments need to be more proactive in establishing guidelines and protocols in safety, including the specific equipment to use with various handling activities. Safety and manufacturing companies like 3M have increasingly become aware of this need, recommending procedures and personal protective equipment for cannabis handling tasks. And Colorado's Department of Public Health & Environment have created their own guidance called Guide to Worker Safety and Health in the Marijuana Industry. However, whether or not handling of cannabis requires special occupational safety rules has been debated before by various states, with California in 2017 stating existing rules cover the industry adequately. It remains to be seen if states will eventually create their own occupational rules as the industry expands further.
5.4 Big Marijuana
Both U.S. states and the federal government have a long, sometimes torturous history with regulating and controlling the production and sale of drug-containing products such as pharmaceuticals, tobacco, beer, wine, and spirits. As such, it seems intuitive to examine the successes and failures of those past efforts when considering what to do with cannabis. One aspect of that examination that raises concern among some is the likelihood of a narrow group of commercial interests taking over all aspects of cannabis production, testing, distribution, and sales. Taking from "Big Pharma," "Big Tobacco," and "Big Alcohol," some fear a similar "Big Marijuana" industry will develop. These fears can be found among small private growers at the hyper-local level, all the way up to the state government level.
In fact, in a 2015 Pathways Report, the state of California—including its Lt. Governor Gavin Newsom—expressed this very concern in regards to how best to regulate marijuana in the state. When considering the marijuana industry structure, they found that controls should be put in place to better incentivize smaller industry players, stating "[t]he goal should be to prevent the growth of a large, corporate marijuana industry dominated by a small number of players, as we see with Big Tobacco or the alcohol industry." Despite that advice, major California-based industry players such as Steve DeAngelo—who owns one of the largest medical marijuana dispensaries in the world and co-founded Steep Hill Labs—remain concerned that mandates for distribution, which mirror alcohol regulations, will only undermine small cannabis businesses in the state.
Anti-marijuana alliances such as Smart Approaches to Marijuana (SAM) and corporation-friendly pro-cannabis Marijuana Policy Project (MPP) act as opposing special interest groups, one fighting against Big Marijuana, the other borrowing from a libertarian approach proposing regulation of marijuana in a way similar to alcohol. These and other special interest groups inevitably bring about the perception that, as the Brookings Institution puts it, "the marijuana industry is as self-serving as any other commercial lobby," further propelling worries of Big Marijuana.
If worries of large corporations taking over significant portions of cannabis production, testing, distribution, and sales markets actually come to fruition, how will they potentially manifest? The previously mentioned concern of increased consolidation of testing labs is arguably one sign, as is DeAngelo's concern of forced distribution contracts taking away from smaller businesses. Brookings also points out concerns of large firms gaining hold over the evolving regulatory status as well as upward trends in antisocial marketing, though they also argue against undue alarmism of commercialization at the same time. David Boaz of the Cato Institute also speaks of regulatory status, though from the standpoint of regulations being "more burdensome on newer and smaller companies than on large, established companies," furthering the idea of Big Marijuana being able to weather the storm better than small, independent operations.
Another manifestation of how Big Marijuana may be taking hold is through the patenting of cannabis strains and methods. PBS' Nova reported in October 2016 that a group of California growers were granted a patent for "compositions and methods for the breeding, production, processing and use of specialty cannabis," raising concerns about how Big Pharma could capitalize. Mowgli Holmes—founder of Phylos Biosciences, a genetics testing laboratory for cannabis—says as much: "Everyone is terrified of some big corporation with deep pockets coming in and taking over ... and they should be." To fight against the misappropriation of patents for "public domain" cannabis strains, he and others have developed Phylos Galaxy to better track relations between existing cannabis strains and the creation of new strains. From a lab testing perspective, a small but increasing number of qualified labs could test not only for potency, terpenes, and pesticides but also genetically verify in a standardized format that a unique strain is actually what it is claimed to be, providing slight competitive advantage. Similar efforts were being spearheaded by the Open Cannabis Project, which had been encouraging others to store genetic data for natural and previously available varieties in efforts to make them unpatentable. However, the Open Cannabis Project dissolved in May 2019 due to controversy surrounding its association with Phylos Bioscience and Phylos' perceived abuse of the provided open data.
Despite the protests against patenting cannabis strains, overall cannabis patenting continues to trend upwards in the U.S. According to Reuters, approved patents containing the word "cannabis" numbered 14 in 2016, 29 in 2017, and 39 as of late November 2018. Of course, many more applied, with 767 U.S. patent filings occurring between 2016 and 2018 (reportedly 1.5 times more than files from 2013 to 2015). In 2019, this showed no signs of stopping. In particular, approved patent filings for cannabis extraction technologies alone numbered 30 by early December, with "many others related to distillation of cannabinoid components and techniques for obtaining active compounds from marijuana and hemp."
Also notable is the first real patent infringement case related to cannabis, a case that could have particularly negative ramifications for the future of the cannabis industry. United Cannabis Corporation v. Pure Hemp Collective, Inc. was filed in 2018 as a patent infringement case on United Cannabis' liquid cannabinoid formulations. A new wrinkle arose in early 2019, when Pure Hemp Collective filed a counterclaim for prior art, a claim that attorney Jihee Ahn finds interesting:
Of course, it remains to be seen exactly what Pure Hemp plans to offer in support of its prior art argument. Typically, defendants in patent litigation produce years, sometimes decades, of scientific articles and other writings to demonstrate a given industry’s preexisting research and knowledge. It’s clear this wealth of evidence likely doesn’t exist for Pure Hemp given the general illegality of marijuana to date. This means the prior art could definitely be out there, but hard to definitively prove given that it was driven underground.
Yet some legal experts question the validity of United Cannabis' initial patent, with IP watchdog Steve Brachmann going so far as to say "I don’t understand how that could be considered patentable." Brachmann also spoke about the issues of prior art, noting "you don't really find prior art outside of High Times magazine," painting a similar veneer of doubt on Pure Hemp's counterclaim. With others such as Molson Coors Brewing and Coca-Cola stepping foot into or considering attempting to get into CBD formulations, this case deserves further watching as it may very well have a dampening affect on further cannabis-based patenting. As this and other intellectual property wars over strains, methods, and formulas get more heated, it remains to be seen how the laboratory testing, research and development, and production environments in the cannabis industry will further take shape.
5.5 Non-U.S. policy
Aside from a few mentions of Canada and European regulation, this guide has focused solely on the state of cannabis and related lab testing in the United States. However, it would be remiss to not look at how policy elsewhere may potentially impact the U.S. cannabis market, if nothing else at least indirectly. Broadly speaking, other countries like the Netherlands and Portugal have put more emphasis on decriminalization and recreational legalization of marijuana than on researching and providing marijuana for medical purposes. Israel has been one of the major exceptions to this generalization, arguably "up to 10 years ahead of other countries in innovation in the cannabis industry." The country has been involved with cannabis research since the 1960s, and today it has its hands in many medical research-based initiatives (though recreational marijuana is still illegal), including:
- The Green Book, a set of written protocols and policy detailing how doctors should work with medical marijuana as well as how it would be commercialized across the country; includes training and certification of 100 doctors for prescribing it
- the creation of the Medical Cannabis Unit, a government agency that regulates medical cannabis research and use
- the development of significant investment and infrastructure for clinical trials involving medical cannabis
- the development of a national institute for medical marijuana research
- the discussion of potentially exporting cannabis and/or cannabis-related extracts and derivatives
- several higher education facilities offering courses and research opportunities on cannabis
- several start-ups developing improved cultivation, pharmaceutical, and medical device technology
Another major country challenging traditional cannabis regulation is Uruguay, which in December 2013 adopted the first stages of regulatory legislation that would ultimately make the cultivation, sale, and use (recreational and medical) of cannabis in the country legal and government-controlled. In part due to concerns regarding gang-related violence and a tentative but not proven connection to black-market cannabis, the country has since carefully and methodically implemented the laws and regulations with the goal of keeping in mind evidence-based research and the potential social impact. In fact, a late February 2017 press release from Canadian company Emblem Corp. stated it and Uruguayan ICC International Cannabis Corporation would, pending finalization of regulatory processes between the two countries, begin a partnership that would have Emblem import CBD (cannabidiol) from ICC "to help fulfill the demand in the Canadian market." The end result has been a growing body of evidence that the cannabis policies are working intended and that they can provide guidance to other countries seeking to legalize some aspects of cannabis, or even begin exporting it as a crop.
The reality of all this—combined with the legalization momentum in the U.S. and other neighboring countries like Canada (the first G-7 nation to end marijuana prohibition) and Mexico—means that new pressures are being applied to organizers of international treaties and policy, and any future changes to those treaties and policy may inversely apply pressure back on the U.S. government to update its stance on cannabis. An October 2014 Brookings Institution interview revealed some of the issues "straining the limits of an international drug control regime that most participants, including the United States, have long understood to be quite strict." Drug treaties such as the Single Convention on Narcotic Drugs (1961), Convention on Psychotropic Substances (1971), and United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances (1988) represent hard policy that the U.S. government (as well as other federal governments) has followed steadfastly for years. However, a dichotomy begins to form when federal governments bend those treaties either through outright legalization or, as is the case in the U.S., by allowing the states power to determine their own laws.
As a result of these stresses, policy experts around the world have been shining light on the need for not only federal governments but also international agencies such as the United Nations' World Health Organisation (WHO) to move forward with critical reviews of existing cannabis research in the social and medical domains and determine if revising cannabis' scheduling is appropriate. Additionally, policy experts have urged United Nations members to discuss and amend existing treaties, even if such amendments only provide greater flexibility in regards to marijuana. That applied pressure has seemingly turned into action by the WHO and the European Union. In February 2019, the WHO recommended the rescheduling of cannabis under international drug treaties, removing cannabis and THC from Schedule IV (the most restrictive classification of drugs) of the 1961 Single Convention on Narcotic Drugs and kept at Schedule I, with extracts and tinctures being removed entirely from scheduling. The WHO also recommended CBD to be removed from the list of schedules. The European Union encouraged its members to vote in favor of the WHO recommendations,  and members of the United Nations Commission on Narcotic Drugs (CND) ended up voting in favor of WHO Recommendation 5.1 to delete cannabis and cannabis resin from Schedule IV of the 1961 Convention. Optimistically, that action could be enough to "encourage countries to reevaluate how cannabis is classified on their own lists of narcotic drugs, potentially paving the way for more research into medical marijuana and its use as a treatment for a variety of ailments and conditions," further shaping how international cannabis businesses conduct business.
Whether or not the decriminalization, rescheduling, and legalization efforts of Israel, the Netherlands, Uruguay, and other global entities such as the WHO has a noticeable impact on international and U.S. federal law remains to be seen. However, it would be foolish to entirely ignore foreign policy when considering the future of cannabis in the United States.
- ↑ Newport, F. (10 December 2012). "Americans Want Federal Gov't Out of State Marijuana Laws". Gallup, Inc. https://news.gallup.com/poll/159152/americans-federal-gov-state-marijuana-laws.aspx. Retrieved 05 August 2022.
- ↑ "Republicans Out Of Step With U.S. Voters On Key Issues, Quinnipiac University National Poll Finds; Most Voters Support Legalized Marijuana". Quinnipiac University. 23 February 2017. Archived from the original on 28 July 2020. https://web.archive.org/web/20200728040818/https://poll.qu.edu/national/release-detail?ReleaseID=2432. Retrieved 05 August 2022.
- ↑ "Support for Legal Marijuana Holds at Record High of 68%". Gallup. 4 November 2021. https://news.gallup.com/poll/356939/support-legal-marijuana-holds-record-high.aspx. Retrieved 05 August 2022.
- ↑ 4.0 4.1 4.2 Romza-Kutz, D.; Roth V., F. (15 August 2016). "The silver lining in the DEA’s refusal to reclassify cannabis". Tracking Cannabis. Thompson Coburn LLP. https://www.thompsoncoburn.com/insights/blogs/tracking-cannabis/post/2016-08-15/the-silver-lining-in-the-dea-s-refusal-to-reclassify-cannabis. Retrieved 05 August 2022.
- ↑ Hellerman, C. (8 March 2017). "Scientists say the government’s only pot farm has moldy samples — and no federal testing standards". PBS NewsHour. NewsHour Productions, LLC. https://www.pbs.org/newshour/nation/scientists-say-governments-pot-farm-moldy-samples-no-guidelines. Retrieved 05 August 2022.
- ↑ "Applications To Become Registered Under the Controlled Substances Act To Manufacture Marijuana To Supply Researchers in the United States". Federal Register 81 (156): 53846–8. 12 August 2016. https://www.federalregister.gov/documents/2016/08/12/2016-17955/applications-to-become-registered-under-the-controlled-substances-act-to-manufacture-marijuana-to. Retrieved 05 August 2022.
- ↑ Smith, J. (15 January 2020). "US House panel calls for stepped-up marijuana research, which could prove critical to federal reform". Marijuana Business Daily. https://mjbizdaily.com/us-house-panel-calls-for-stepped-up-marijuana-research-which-could-prove-critical-to-federal-reform/. Retrieved 05 August 2022.
- ↑ 8.0 8.1 Diversion Control Division (18 December 2020). "Marihuana Growers Information". U.S. Drug Enforcement Administration. https://www.deadiversion.usdoj.gov/drugreg/marihuana.htm. Retrieved 05 August 2022.
- ↑ 13 April 2022. "Can DEA-backed cannabis growers strike gold via drug development?". https://mjbizdaily.com/dea-backed-cannabis-growers-seek-to-strike-gold-via-drug-development/. Retrieved 05 August 2022.
- ↑ 10.0 10.1 Weiss, S.R.B. (13 July 2016). "Testimony from Susan R.B. Weiss, Ph.D. on The State of the Science on the Therapeutic Potential of Marijuana and Cannabinoids before Judiciary Committee". ASL Testimony. U.S. Department of Health & Human Services. Archived from the original on 04 May 2017. https://web.archive.org/web/20170504180135/https://www.hhs.gov/about/agencies/asl/testimony/2016-09/the-state-of-the-science-on-the-therapeutic-potential-of-marijuana-and-cannabinoids/index.html. Retrieved 05 August 2022.
- ↑ Weiss, S.R.B.; Howlett, K.D.; Baler, R.D. (2017). "Building smart cannabis policy from the science up". International Journal of Drug Policy 42: 39–49. doi:10.1016/j.drugpo.2017.01.007. PMC PMC5404989. PMID 28189459. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=PMC5404989.
- ↑ National Academies of Sciences, Engineering, and Medicine (12 January 2017). "The health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research". The National Academies Press. pp. 440. doi:10.17226/24625. https://nap.nationalacademies.org/catalog/24625/the-health-effects-of-cannabis-and-cannabinoids-the-current-state. Retrieved 03 March 2017.
- ↑ National Institute on Drug Abuse (6 February 2018). "Recommendations for NIDA's Cannabis Policy Research Agenda" (PDF). National Institutes of Health. https://nida.nih.gov/sites/default/files/nacda_cannabis_policy_research_workgroup_report_feb_2018.pdf. Retrieved 05 August 2022.
- ↑ National Institute on Drug Abuse (July 2020). "Cannabis (Marijuana) Research Report". National Institutes of Health. https://nida.nih.gov/publications/research-reports/marijuana/letter-director. Retrieved 05 August 2022.
- ↑ National Institute on Drug Abuse (27 March 2020). "NIDA's Role in Providing Cannabis for Research". National Institutes of Health. https://nida.nih.gov/research-topics/marijuana/nidas-role-in-providing-cannabis-research. Retrieved 05 August 2022.
- ↑ 16.0 16.1 16.2 O’Grady, Cathleen (27 August 2020). "Cannabis research database shows how U.S. funding focuses on harms of the drug". Science. doi:10.1126/science.abe5328. ISSN 0036-8075. https://www.sciencemag.org/news/2020/08/cannabis-research-database-shows-how-us-funding-focuses-harms-drug.
- ↑ "Marijuana research". Colorado Department of Public Health & Environment. https://cdphe.colorado.gov/prevention-and-wellness/marijuana/marijuana-research. Retrieved 05 August 2022.
- ↑ American Public Health Association (24 October 2020). "A Public Health Approach to Regulating Commercially Legalized Cannabis". https://www.apha.org/Policies-and-Advocacy/Public-Health-Policy-Statements/Policy-Database/2021/01/13/A-Public-Health-Approach-to-Regulating-Commercially-Legalized-Cannabis. Retrieved 05 August 2020.
- ↑ Stith, Sarah See; Vigil, Jacob Miguel (3 June 2016). "Federal barriers to Cannabis research" (in en). Science 352 (6290): 1182–1182. doi:10.1126/science.aaf7450. ISSN 0036-8075. https://www.science.org/doi/10.1126/science.aaf7450.
- ↑ Haney, Margaret (1 October 2020). "Perspectives on Cannabis Research—Barriers and Recommendations" (in en). JAMA Psychiatry 77 (10): 994. doi:10.1001/jamapsychiatry.2020.1032. ISSN 2168-622X. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2767410.
- ↑ Cooper, Ziva D; Abrams, Donald I; Gust, Steven; Salicrup, Alejandro; Throckmorton, Douglas C (28 November 2021). "Challenges for Clinical Cannabis and Cannabinoid Research in the United States" (in en). JNCI Monographs 2021 (58): 114–122. doi:10.1093/jncimonographs/lgab009. ISSN 1052-6773. PMC PMC8783595. PMID 34850896. https://academic.oup.com/jncimono/article/2021/58/114/6446199.
- ↑ Ruheel, Mohammad Ali; Gomes, Zoya; Usman, Sana; Homayouni, Pargol; Ng, Jeremy Y. (1 December 2021). "Facilitators and barriers to the regulation of medical cannabis: a scoping review of the peer-reviewed literature" (in en). Harm Reduction Journal 18 (1): 106. doi:10.1186/s12954-021-00547-8. ISSN 1477-7517. PMC PMC8515704. PMID 34649577. https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00547-8.
- ↑ Grant, B. (23 January 2017). "Marijuana Research Still Stymied by Federal Laws". The Scientist. LabX Media Group. https://www.the-scientist.com/news-opinion/marijuana-research-still-stymied-by-federal-laws-32161. Retrieved 08 August 2022.
- ↑ Morris, C. (21 October 2016). "The next big billion-dollar cannabis markets investors are rushing to". CNBC. http://www.cnbc.com/2016/10/21/the-next-big-billion-dollar-cannabis-markets-investors-are-rushing-to.html. Retrieved 08 August 2022.
- ↑ Thomas, J.R. (7 February 2017). "Big pot of money waiting if CT legalizes marijuana, analysts say". The CT Mirror. The Connecticut News Project. https://ctmirror.org/2017/02/07/big-pot-of-money-waiting-if-ct-legalizes-marijuana-analysts-say/. Retrieved 08 August 2022.
- ↑ Houghton, S. (14 February 2017). "Town Manager: Marijuana Shops Could Boost Tax Revenue". The Mashpee Enterprise. Enterprise Newspapers. http://www.capenews.net/mashpee/news/town-manager-marijuana-shops-could-boost-tax-revenue/article_c27b9b71-fb63-52de-bc24-fda320f38a32.html. Retrieved 08 August 2022.
- ↑ 27.0 27.1 27.2 27.3 Wallace, A. (22 February 2017). "Report: America’s marijuana industry headed for $24 billion by 2025". The Cannabist. The Denver Post. http://www.thecannabist.co/2017/02/22/report-united-states-marijuana-sales-projections-2025/74059/. Retrieved 08 August 2022.
- ↑ Grand View Research, Inc (15 June 2022). "U.S. Cannabis Market to be Worth $40.0 Billion by 2030: Grand View Research, Inc.". PR Newswire. https://www.prnewswire.com/news-releases/us-cannabis-market-to-be-worth-40-0-billion-by-2030-grand-view-research-inc-301568650.html. Retrieved 08 August 2022.
- ↑ 29.0 29.1 Wallace, A. (22 December 2016). "What legal states need to know about sketchy pot tax predictions". The Cannabist. The Denver Post. http://www.thecannabist.co/2016/12/22/marijuana-sales-pot-taxes-colorado-estimates-projections/69831/. Retrieved 08 August 2022.
- ↑ Potter, K. (12 August 2016). "Big losses for Minn. medical marijuana providers". MPR News. Minnesota Public Radio. https://www.mprnews.org/story/2016/08/12/big-losses-for-minn-medical-marijuana-providers. Retrieved 08 August 2022.
- ↑ 31.0 31.1 31.2 Piomelli, D.; Weiss, S.; Boyd, G. et al. (2018). "Cannabis and the Opioid Crisis". Cannabis and Cannabinoid Research 3 (1): 108-16. doi:10.1089/can.2018.29011.rtl. PMC PMC5931647. PMID 29789812. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=PMC5931647.
- ↑ Bradford, A.S.; Abraham, A.; Adams, G.B. (2018). "Opioid Death Rate Acceleration in Jurisdictions Legalizing Marijuana Use—Reply". JAMA Internal Medicine 178 (9): 1281–2. doi:10.1001/jamainternmed.2018.3891.
- ↑ Goldman, H. (13 July 2018). "New York Health Officials See Marijuana as an Alternative to Opioids". Bloomberg. https://www.bloomberg.com/news/articles/2018-07-13/n-y-health-officials-see-marijuana-as-an-alternative-to-opioids. Retrieved 08 August 2022.
- ↑ Sukel, K. (1 May 2018). "Could Cannabis Legalization Help Ease the Opioid Crisis?". Pain Research Forum. International Association for the Study of Pain. https://www.painresearchforum.org/news/95694-could-cannabis-legalization-help-ease-opioid-crisis. Retrieved 08 August 2022.
- ↑ "Unproven, Unsafe". Spotlight PA. 21 February 2022. https://www.spotlightpa.org/news/2022/02/pennsylvania-medical-marijuana-addiction-misleading-dangerous-websites/. Retrieved 08 August 2022.
- ↑ 36.0 36.1 "S.1456 - Marijuana Data Collection Act". Congress.gov. U.S. Government. 29 April 2021. https://www.congress.gov/bill/117th-congress/senate-bill/1456. Retrieved 08 August 2022.
- ↑ Angell, T. (24 July 2018). "Federal Report On Marijuana Legalization Required Under New Bill". Forbes. https://www.forbes.com/sites/tomangell/2018/07/24/federal-report-on-marijuana-legalization-required-under-new-bill/#41b953e73532. Retrieved 08 August 2022.
- ↑ "U.S. Cannabis Testing Market". Global Market Insights, Inc. January 2021. https://www.gminsights.com/industry-analysis/us-cannabis-testing-market. Retrieved 09 August 2022.
- ↑ "Cannabis Testing Market". Global Market Insights, Inc. October 2021. https://www.gminsights.com/industry-analysis/cannabis-testing-market. Retrieved 09 August 2022.
- ↑ "Cannabis Testing Services Market Analysis". Coherent Market Insights. July 2022. https://www.coherentmarketinsights.com/market-insight/cannabis-testing-services-market-2976. Retrieved 09 August 2022.
- ↑ Kuzdzal, S.; Clifford, R.; Winkler, P.; Bankert, W. (December 2017). "A Closer Look at Cannabis Testing" (PDF). Shimadzu Corporation. Archived from the original on 07 December 2018. https://web.archive.org/web/20181207195155/https://www.ssi.shimadzu.com/sites/ssi.shimadzu.com/files/Industry/Literature/Shimadzu_Whitepaper_Emerging_Cannabis_Industry.pdf. Retrieved 09 August 2022.
- ↑ 42.0 42.1 Nelson, S. (3 August 2016). "Has Lab Testing Turned A Corner?". Cannabis Business Times. GIE Media, Inc. https://www.cannabisbusinesstimes.com/article/has-lab-testing-turned-a-corner/. Retrieved 09 August 2022.
- ↑ "New Certification Program Brings Quality Assurance to the Medical Marijuana Industry". Information Forecast, Inc. 2016. https://infocastinc.com/market-insights/new-certification-program-brings-quality-assurance-to-the-medical-marijuana-industry/. Retrieved 09 August 2022.
- ↑ Cannabis Committee, AHPA (2 February 2016). "Recommendations for Regulators – Cannabis Operations" (PDF). American Herbal Products Association. https://www.ahpa.org/Portals/0/pdfs/AHPA_Recommendations_for_Regulators_Cannabis_Operations.pdf. Retrieved 09 August.
- ↑ Upton, R.; Craker, L.; ElSohly, M. et al., ed. (2014). Cannabis Inflorescence: Cannabis spp.. American Herbal Pharmacopoeia. ISBN 1929425333. https://herbal-ahp.org/online-ordering-cannabis-inflorescence-qc-monograph/.
- ↑ Project CBD; Marcu, J. (16 March 2016). "Cannabis Lab Testing & Safety Protocols". Project CBD. Project CBD. https://www.projectcbd.org/industry/cannabis-lab-testing-safety-protocols. Retrieved 09 August 2022.
- ↑ Erickson, B.E. (13 November 2017). "Cleaning up cannabis". Chemical & Engineering News. American Chemical Society. https://cen.acs.org/articles/95/i45/Cleaning-cannabis.html. Retrieved 09 August.
- ↑ Cassiday, L. (October 2016). "The Highs and Lows of Cannabis Testing". INFORM. American Oil Chemists' Society. https://www.aocs.org/stay-informed/inform-magazine/featured-articles/the-highs-and-lows-of-cannabis-testing-october-2016. Retrieved 09 August 2022.
- ↑ Association of Public Health Laboratories (May 2016). "Guidance for State Medical Cannabis Testing Programs" (PDF). pp. 35. https://www.aphl.org/aboutAPHL/publications/Documents/EH-Guide-State-Med-Cannabis-052016.pdf. Retrieved 09 August 2022.
- ↑ Association of Official Agricultural Chemists (12 November 2019). "New guidelines require laboratories to meet AOAC Standard Method Performance Requirements for Quantitation of Cannabinoids in Hemp". AOAC News. https://www.aoac.org/news/aoac-cannabinoid-standard-in-usda-guidelines/. Retrieved 09 August 2022.
- ↑ "Committee D37 on Cannabis". ASTM International. https://www.astm.org/get-involved/technical-committees/committee-d37. Retrieved 08 July 2022.
- ↑ "The Emerald Test". Emerald Scientific, LLC. https://pt.emeraldscientific.com/. Retrieved 09 August 2022.
- ↑ Scholl, C. (2020). "Automating a Cannabis Testing Laboratory" (PDF). Cannalysis. https://biosero.com/wp-content/uploads/2021/07/SLAS-Biosero-Tutorial-2020_Chris-Scholl.pdf. Retrieved 09 August 2022.
- ↑ Goldman, S. (27 January 2021). "Automation in the Cannabis & Hemp Testing Laboratories of Tomorrow". Analytical Cannabis. https://go.analyticalcannabis.com/cannabis-automation. Retrieved 09 August 2022.
- ↑ Astill, T. (4 April 2022). "Automating Testing Accelerated Results: How Best Practices in Cannabis Analysis Innovation are Enhancing Safety and Quality". Terpenes and Testing Magazine. https://terpenesandtesting.com/automating-testing-accelerated-results-how-best-practices-in-cannabis-analysis-innovation-are-enhancing-safety-and-quality/. Retrieved 09 August 2022.
- ↑ 56.0 56.1 Ross, K. (4 May 2022). "How Cannabis Labs Can Benefit From Data and Process Automation". Analytical Cannabis. https://www.analyticalcannabis.com/articles/how-cannabis-labs-can-benefit-from-data-and-process-automation-313857. Retrieved 09 August 2022.
- ↑ 57.0 57.1 Ross, K. (13 June 2022). "The Promising Future of Cannabis Testing Laboratories". Analytical Cannabis. https://www.analyticalcannabis.com/articles/the-promising-future-of-cannabis-testing-laboratories-313955. Retrieved 09 August 2022.
- ↑ Bilyj, B. (23 November 2021). "The Costs and Benefits of Automation in Cannabis Cultivation". Cannabis Business Times. https://www.cannabisbusinesstimes.com/article/the-costs-and-benefits-of-automation-cannabis-cultivation/. Retrieved 09 August 2022.
- ↑ Lampach, D. (20 November 2013). "Q&A With CEO of Steep Hill Halent: US Cannabis Testing Market Could Hit $40M by 2016". Marijuana Business Daily. Anne Holland Ventures, Inc. https://mjbizdaily.com/qa-with-steep-hill-lab-ceo-david-lampach-cannabis-testing-market-could-hit-40m-in-2-years/. Retrieved 09 August 2022.
- ↑ CannabisFN (16 July 2015). "DigiPath (DIGP) Well Positioned To Take Advantage of $850M Cannabis Testing Market". The Marijuana Index. MJIC, Inc. Archived from the original on 06 August 2020. http://marijuanaindex.com/digipath-digp-well-positioned-to-take-advantage-of-850m-cannabis-testing-market/. Retrieved 09 August 2022.
- ↑ Schroyer, J. (January 2016). "Industry Snapshot: Testing Labs". Marijuana Business Magazine. Anne Holland Ventures, Inc. https://mjbizmagazine.com/industry-snapshot-testing-labs/. Retrieved 09 August 2022.
- ↑ "5 Key Things to Know About the Cannabis Testing Laboratory Business in California". Insights. Kramer Holcomb Sheik LLP. July 2018. Archived from the original on 15 February 2020. https://web.archive.org/web/20200215103305/https://www.khslaw.com/insights/cannabis-testing-lab-laws-in-california/. Retrieved 09 August 2022.
- ↑ Schroyer, J. (7 October 2019). "Life has stabilized for California marijuana testing labs since 2018, but hurdles remain". Marijuana Business Daily. https://mjbizdaily.com/life-has-stabilized-for-california-testing-labs-since-2018-but-hurdles-remain/. Retrieved 09 August 2022.
- ↑ Bennett, N. (30 April 2019). "Consolidation trend shows cannabis growers are buying labs". BIV. https://biv.com/article/2019/04/consolidation-trend-shows-cannabis-growers-are-buying-labs. Retrieved 09 August 2022.
- ↑ Pletz, J. (3 May 2019). "Merger madness reshapes marijuana business". Chicago Business. https://www.chicagobusiness.com/news/merger-madness-reshapes-marijuana-business. Retrieved 09 August 2022.
- ↑ 66.0 66.1 Owens, B. (21 June 2016). "How Space Technology Will Produce the Best Weed Ever". Motherboard. Motherboard-IPTV LLC. https://www.vice.com/en/article/8q85qk/how-space-technology-will-produce-the-best-weed-marijuana-cannabis-pot. Retrieved 09 August 2022.
- ↑ Gustafson, K. (7 December 2016). "Startup Launches Automated System It Claims Makes It Easy To Grow Marijuana At Home". Forbes. Forbes.com LLC. https://www.forbes.com/sites/katherinegustafson/2016/12/07/it-just-became-incredibly-easy-to-grow-marijuana-at-home-meet-leaf/print/. Retrieved 09 August 2022.
- ↑ Solomon, S. (9 November 2016). "Israeli startup creates idiot’s guide to home-grown food". The Times of Israel. http://www.timesofisrael.com/israeli-startup-creates-idiots-guide-to-home-grown-food/. Retrieved 09 August 2022.
- ↑ 69.0 69.1 69.2 Press, V.S. (13 February 2017). "5 reasons Israel is dominating the cannabis industry". ISREAL21c. https://www.israel21c.org/5-reasons-israel-is-dominating-the-cannabis-industry/. Retrieved 09 August 2022.
- ↑ Wenkert, A.; Hirschauge, O. (13 February 2018). "Leaf, Long-Awaited Home Cannabis Farming Box, to Start Shipping". CTech. Yedioth Ahronoth Group. https://www.calcalistech.com/ctech/articles/0,7340,L-3731790,00.html. Retrieved 09 August 2022.
- ↑ Schiller, M. (4 June 2018). "Front Range Biosciences Offers Clean Stock Program for Cannabis to Reduce Loss and Increase Efficiency". Cannabis Business Times. GIE Media, Inc. https://www.cannabisbusinesstimes.com/article/front-range-biosciences-offers-clean-stock-program-cannabis/. Retrieved 09 August 2022.
- ↑ "Front Range Biosciences' Clean Stock® Program Fights Hop Latent Viroid in Cannabis". Front Range Biosciences. 20 May 2021. https://www.frontrangebio.com/posts/front-range-biosciences-clean-stock-r-program-fights-hop-latent-viroid-in-cannabis. Retrieved 09 August 2022.
- ↑ 73.0 73.1 Trager, R. (22 August 2018). "Accidents at cannabis cultivation facilities worry industry chemists". Chemistry World. Royal Society of Chemistry. https://www.chemistryworld.com/news/accidents-at-cannabis-cultivation-facilities-worry-industry-chemists/3009412.article. Retrieved 09 August 2022.
- ↑ Davidson, M.; Reed, S.; Oosthuzien, J. et al. (2018). "Occupational health and safety in cannabis production: an Australian perspective". International Journal of Occupational and Environmental Health 24 (3–4): 75–85. doi:10.1080/10773525.2018.1517234. PMC PMC6237171. PMID 30281413. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=PMC6237171.
- ↑ Victory, K.R.; Couch, J.; Lowe, B. et al. (2018). "Notes from the Field: Occupational Hazards Associated with Harvesting and Processing Cannabis — Washington, 2015–2016". Morbidity and Mortality Weekly Report 67: 259–60. doi:10.15585/mmwr.mm6708a7.
- ↑ Valentic, S. (27 March 2018). "Study: Cannabis Workers Value Safety but Lack Formal Training". EHS Today. https://www.ehstoday.com/safety/article/21919561/study-cannabis-workers-value-safety-but-lack-formal-training. Retrieved 09 August 2022.
- ↑ "Growing Worker Safety Concerns in the Medical Marijuana Industry". Worker Health and Safety. 3M. 17 April 2018. https://workersafety.3m.com/growing-worker-safety-concerns-medical-marijuana-industry/. Retrieved 09 August 2022.
- ↑ "Technical Data Bulletin #249 - Legal Cannabis Growing Operations" (PDF). 3M Personal Safety Division. September 2016. http://multimedia.3m.com/mws/media/1283636O/tdb-249-legal-cannabis-growing-operations-pdf.pdf. Retrieved 09 August 2022.
- ↑ Bottino, B. (24 November 2019). "Cannabis work safety". Safety+Health. https://www.safetyandhealthmagazine.com/articles/19117-cannabis-worker-safety. Retrieved 09 August 2022.
- ↑ Bland, K.D. (6 July 2017). "Cal/OSHA Declines to Create Marijuana-Specific Safety Regulations". State and Local Updates. Society for Human Resource Management. Archived from the original on 12 August 2020. https://web.archive.org/web/20200812044233/https://www.shrm.org/resourcesandtools/legal-and-compliance/state-and-local-updates/pages/cal-osha-declines-to-create-marijuana-specific-safety-regulations.aspx. Retrieved 09 August 2022.
- ↑ 81.0 81.1 Hudak, J.; Rauch, J. (June 2016). "Worry about bad marijuana—not Big Marijuana" (PDF). The Brookings Institution. pp. 18. https://www.brookings.edu/wp-content/uploads/2016/07/big-marijuana-1.pdf. Retrieved 09 August 2022.
- ↑ Sullivan, J. (8 November 2018). "‘Big Marijuana’ is actually a thing". CommonWealth. Mass Inc. https://commonwealthmagazine.org/back-story/big-marijuana-is-actually-a-thing/. Retrieved 09 August 2022.
- ↑ 83.0 83.1 83.2 Solovitch, S. (29 August 2016). "How Big Alcohol Is About to Get Rich Off California Weed". POLITICO. POLITICO, LLC. http://www.politico.com/magazine/story/2016/08/marijuana-legalization-big-business-alcohol-214198. Retrieved 09 August 2022.
- ↑ 84.0 84.1 Steering Committee of the Blue Ribbon Commission on Marijuana Policy (22 July 2015). "Pathways Report: Policy Options for Regulating Marijuana in California" (PDF). Blue Ribbon Commission on Marijuana Policy. https://www.aclunc.org/sites/default/files/20150721-brc_pathways_report.pdf. Retrieved 09 August 2022.
- ↑ 85.0 85.1 Wallach, P.; Rauch, J. (June 2016). "Bootleggers, Baptists, bureaucrats, and bongs: How special interests will shape marijuana legalization" (PDF). The Brookings Institution. pp. 22. https://www.brookings.edu/wp-content/uploads/2016/07/bootleggers.pdf. Retrieved 09 August 2022.
- ↑ "The Money in Marijuana: The political landscape". OpenSecrets.org. Center for Responsive Politics. November 2015. https://www.opensecrets.org/news/issues/marijuana/. Retrieved 09 August 2022.
- ↑ Boaz, D. (25 April 2018). "Will Regulations Create Big Marijuana?". Cato at Liberty. Cato Institute. https://www.cato.org/blog/will-regulations-create-big-marijuana. Retrieved 09 August 2022.
- ↑ 88.0 88.1 Arnold, C. (19 October 2016). "The Rise of Marijuana™ (Patent Pending)". Nova Next. PBS. https://www.pbs.org/wgbh/nova/article/patenting-pot/. Retrieved 09 August 2022.
- ↑ Canna Law Blog (23 February 2018). "Open Cannabis Project: The Fight to Get Marijuana Patents Right". Canna Law Blog. Harris Bricken. https://harrisbricken.com/cannalawblog/open-cannabis-project-and-the/. Retrieved 09 AUgust 2022.
- ↑ Shepherd, K. (6 May 2019). "Open Cannabis Project Dissolves In Response to Controversy Over Ag-Science Company Phylos Bioscience’s Breeding Program". Willamette Week. https://www.wweek.com/news/business/2019/05/06/open-cannabis-project-dissolves-in-response-to-controversy-over-ag-science-company-phylos-biosciences-breeding-program/. Retrieved 09 August 2022.
- ↑ Brachmann, S. (26 July 2019). "U.S. Cannabis Inventions Grow". Inventors Digest. https://www.inventorsdigest.com/articles/u-s-cannabis-inventions-grow/. Retrieved 09 AUgust 2022.
- ↑ Nayak, M. (1 August 2019). "Cannabis Companies Gamble on Patents to Lure Possible Suitors". Bloomberg Law. https://news.bloomberglaw.com/ip-law/cannabis-companies-gamble-on-patents-to-lure-possible-suitors. Retrieved 09 August 2022.
- ↑ Kamps, M. (10 October 2019). "The Number of Cannabis-Centric Patents Is Getting High". Law360. https://www.law360.com/articles/1206064. Retrieved 09 August 2022.
- ↑ 94.0 94.1 Capuano, V. (5 December 2019). "2019 Cannabis Patent Review I: Extraction and Purification". LinkedIn Pulse. Archived from the original on 26 February 2020. https://web.archive.org/web/20200226172321/https://www.linkedin.com/pulse/2019-cannabis-patent-review-i-extraction-purification-vince-capuano/. Retrieved 09 August 2022.
- ↑ 95.0 95.1 95.2 Maxfield, A. (2019). "Intellectual Property Survey: Cannabis Plant Types, Methods of Extraction, IP Protection, and One Patent That Could Ruin It All". Drug Enforcement and Policy Center 3: 1–8. doi:10.2139/ssrn.3376060.
- ↑ 96.0 96.1 Ahn, J. (4 March 2019). "Cannabis Patent Litigation Update: Is Extraction and Preparation Prior Art?". Canna Law Blow. https://www.cannalawblog.com/cannabis-patent-litigation-update-is-extraction-and-preparation-prior-art/. Retrieved 09 August 2022.
- ↑ Johnson, R.M.; Fariman, B.; Gilreath, T. et al. (2015). "Past 15-year trends in adolescent marijuana use: Differences by race/ethnicity and sex". Drug and Alcohol Dependence 155: 8–15. doi:10.1016/j.drugalcdep.2015.08.025. PMC PMC4582007. PMID 26361714. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=PMC4582007.
- ↑ Kershner, I. (17 December 2016). "Israel, a Medical Marijuana Pioneer, Is Eager to Capitalize". The New York Times. The New York Times Company. https://www.nytimes.com/2016/12/17/world/middleeast/israel-a-medical-marijuana-pioneer-is-eager-to-capitalize.html?_r=0. Retrieved 09 August 2022.
- ↑ Efrati, I. (20 October 2016). "Israeli Pharmacies Prepare to Sell Medical Cannabis". Haaretz. Haaretz Daily Newspaper Ltd. https://www.haaretz.com/israel-news/2016-10-20/ty-article/.premium/israeli-pharmacies-prepare-to-sell-medical-cannabis/0000017f-e017-d3ff-a7ff-f1b772e90000. Retrieved 09 August 2022.
- ↑ iCAN Israel (1 September 2016). "Israel: A Peek Inside the Israeli Knesset’s Special Committee on Medical Cannabis". Cannabis Law Journal. http://journal.cannabislaw.report/israel-a-peek-inside-the-israeli-knessets-special-committee-on-medical-cannabis/. Retrieved 09 August 2022.
- ↑ "The Green Book: The Official Guide to Clinical Care in Medical Cannabis". Cannabis Magazine. 6 January 2018. https://www.xn--4dbcyzi5a.com/medical-cannabis-official-israeli-clinical-guide/. Retrieved 09 August 2022.
- ↑ Ramsey, G. (November 2016). "Getting Regulation Right: Assessing Uruguay's Historic Cannabis Initiative" (PDF). WOLA. https://www.wola.org/wp-content/uploads/2016/09/Getting-Regulation-Right-WOLA-Uruguay.pdf. Retrieved 09 August 2022.
- ↑ Reuters (19 July 2017). "Uruguay pharmacies start selling cannabis straight to consumers". The Guardian. https://www.theguardian.com/world/2017/jul/19/uruguay-marijuana-sale-pharmacies. Retrieved 09 August 2022.
- ↑ "Emblem to Import CBD from Uruguay into Canada". New Cannabis Ventures. NCV Media, LLC. 27 February 2017. https://www.newcannabisventures.com/emblem-to-import-cbd-from-uruguay-into-canada/. Retrieved 09 July 2022.
- ↑ Laqueur, Hannah; Rivera-Aguirre, Ariadne; Shev, Aaron; Castillo-Carniglia, Alvaro; Rudolph, Kara E.; Ramirez, Jessica; Martins, Silvia S.; Cerdá, Magdalena (1 June 2020). "The impact of cannabis legalization in Uruguay on adolescent cannabis use" (in en). International Journal of Drug Policy 80: 102748. doi:10.1016/j.drugpo.2020.102748. https://linkinghub.elsevier.com/retrieve/pii/S095539592030089X.
- ↑ Iglesias, M.; Saldías, A.N.; Ross, G. (19 February 2021). "Marijuana: Made in Uruguay". Weekly Asado. https://www.wilsoncenter.org/blog-post/marijuana-made-uruguay. Retrieved 09 August 2022.
- ↑ Tzanis, Z. (20 August 2021). "Benefits of Legalizing Marijuana in Uruguay". The Borgen Project. https://borgenproject.org/legalizing-marijuana-in-uruguay/. Retrieved 09 August 2022.
- ↑ Porter, C. (11 November 2018). "Canada’s Message to Teenagers: Marijuana Is Legal Now. Please Don’t Smoke It". The New York Times. The New York Times Company. https://www.nytimes.com/2018/11/11/world/canada/marijuana-legalization-teenagers.html. Retrieved 09 August 2022.
- ↑ Rogers, K. (24 September 2018). "Eyes of the global marijuana industry are on Canada as it legalizes recreational use". CNBC. https://www.cnbc.com/2018/09/24/eyes-of-the-global-marijuana-industry-are-on-canada-as-it-legalizes-recreational-use.html. Retrieved 09 August 2022.
- ↑ Timmons, P. (31 October 2018). "Mexico's Supreme Court legalizes cannabis for recreational use". UPI. United Press International, Inc. https://www.upi.com/Top_News/World-News/2018/10/31/Mexicos-Supreme-Court-legalizes-cannabis-for-recreational-use/9621541024238/. Retrieved 09 August 2022.
- ↑ 111.0 111.1 111.2 Rauch, J. (16 October 2014). "Marijuana Legalization Poses a Dilemma for International Drug Treaties". Brookings FIXGOV: Making Government Work. The Brookings Institution. https://www.brookings.edu/blog/fixgov/2014/10/16/marijuana-legalization-poses-a-dilemma-for-international-drug-treaties/. Retrieved 09 August 2022.
- ↑ Hamilton, I.; Monaghan, M.; Rolles, S. et al. (23 November 2016). "Why WHO needs a radical rethink of its draconian approach to cannabis". The Conversation. The Conversation US, Inc. https://theconversation.com/why-who-needs-a-radical-rethink-of-its-draconian-approach-to-cannabis-68209. Retrieved 09 August 2022.
- ↑ Sandy, E. (4 February 2019). "World Health Organization Recommends Rescheduling Cannabis Under International Drug Treaties". Cannabis Business Times. https://www.cannabisbusinesstimes.com/article/world-health-organization-recommends-rescheduling-cannabis-thc/. Retrieved 09 August 2022.
- ↑ Schiller, M. (29 January 2020). "European Union Urges Member Nations to Vote for World Health Organization’s Cannabis Rescheduling Recommendations". Cannabis Business Times. https://www.cannabisbusinesstimes.com/article/european-union-urges-member-nations-to-vote-for-world-health-organization-cannabis-rescheduling-recommendations/. Retrieved 27 February 2020.
- ↑ 115.0 115.1 Pascual, A. (17 December 2021). "United Nations approves WHO recommendation to reschedule cannabis in historic vote". MJBiz Daily. https://mjbizdaily.com/united-nations-approves-who-recommendation-to-reschedule-cannabis-in-historic-vote/. Retrieved 09 August 2022.
Citation information for this chapter
Chapter: 5. Future of cannabis regulation, testing, and market trends
Title: Past, Present, and Future of Cannabis Laboratory Testing and Regulation in the United States
Edition: Fourth edition
Author for citation: Shawn E. Douglas
License for content: Creative Commons Attribution-ShareAlike 4.0 International
Publication date: August 2022