Difference between revisions of "Journal:Risk assessment of over-the-counter cannabinoid-based cosmetics: Legal and regulatory issues governing the safety of cannabinoid-based cosmetics in the UAE"
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==Abstract== | ==Abstract== | ||
'''Purpose''': The lack of scientific evidence of the safety and efficacy of over-the-counter topical [[cannabinoid]]-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the United Arab Emirates (UAE) market. In particular, the study attempted to quantify the presence of undeclared [[tetrahydrocannabinol]]—specifically delta-9-tetrahydrocannabinol (Δ<sup>9</sup>-THC) and delta-9-[[tetrahydrocannabinolic acid]] (Δ<sup>9</sup>-THCA)—in these products. | '''Purpose''': The lack of scientific evidence of the safety and efficacy of over-the-counter topical [[cannabinoid]]-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the United Arab Emirates (UAE) market. In particular, the study attempted to quantify the presence of undeclared [[tetrahydrocannabinol]]—specifically delta-9-tetrahydrocannabinol (Δ<sup>9</sup>-THC) and delta-9-[[tetrahydrocannabinolic acid]] (Δ<sup>9</sup>-THCA)—in these products. | ||
'''Methods''': A total of 18 cannabinoid-based cosmetics were collected and analyzed in this study. [[Gas chromatography–mass spectrometry]] (GC-MS) analysis was used to determine the presence of total undeclared tetrahydrocannabinol. | '''Methods''': A total of 18 cannabinoid-based cosmetics were collected and analyzed in this study. [[Gas chromatography–mass spectrometry]] (GC-MS) analysis was used to determine the presence of total undeclared tetrahydrocannabinol. | ||
'''Results''': The estimate for the average tetrahydrocannabinol content was 0.011%, with a 95% CI (0.004−0.019). Leave-on cosmetics products are more likely to contain total tetrahydrocannabinol compared to rinse-off cosmetics (''p'' = 0.041). Although there was no statistically significant difference in the total tetrahydrocannabinol according to cosmetic category, there was a tendency towards higher tetrahydrocannabinol content in hand-care products, baby products, and body care preparations. | |||
'''Conclusion''': The current study reveals the need for producers of cannabinoid-based cosmetic products to issue [[Quality control|quality]] certificates for each batch produced to inform users of the tested levels of tetrahydrocannabinol. | '''Conclusion''': The current study reveals the need for producers of cannabinoid-based cosmetic products to issue [[Quality control|quality]] certificates for each batch produced to inform users of the tested levels of tetrahydrocannabinol. | ||
Revision as of 22:31, 5 July 2021
| Full article title | Risk assessment of over-the-counter cannabinoid-based cosmetics: Legal and regulatory issues governing the safety of cannabinoid-based cosmetics in the UAE |
|---|---|
| Journal | Cosmetics |
| Author(s) | Jairoun, Ammar A.; Al-Hemyari, Sabaa S.; Shahwan, Moyad; Ibrahim, Baharudin; Hassali, Mohamed A.; Zyoud, Sa’ed H. |
| Author affiliation(s) | Universiti Sains Malaysia, Dubai Health and Safety Department, Dubai Ministry of Health and Prevention, Ajman University, Universiti Malaya, An-Najah National University, An-Najah National University Hospital |
| Primary contact | Email: Dr_ammar_91_ at hotmail dot com |
| Editors | Carreño, Amparo S.; Veiga, Juan L.B. |
| Year published | 2021 |
| Volume and issue | 18(3) |
| Article # | 57 |
| DOI | 10.3390/cosmetics8030057 |
| ISSN | 2079-9284 |
| Distribution license | Creative Commons Attribution 4.0 International |
| Website | https://www.mdpi.com/2079-9284/8/3/57/htm |
| Download | https://www.mdpi.com/2079-9284/8/3/57/pdf (PDF) |
 |
This article should be considered a work in progress and incomplete. Consider this article incomplete until this notice is removed. |
Abstract
Purpose: The lack of scientific evidence of the safety and efficacy of over-the-counter topical cannabinoid-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the United Arab Emirates (UAE) market. In particular, the study attempted to quantify the presence of undeclared tetrahydrocannabinol—specifically delta-9-tetrahydrocannabinol (Δ9-THC) and delta-9-tetrahydrocannabinolic acid (Δ9-THCA)—in these products.
Methods: A total of 18 cannabinoid-based cosmetics were collected and analyzed in this study. Gas chromatography–mass spectrometry (GC-MS) analysis was used to determine the presence of total undeclared tetrahydrocannabinol.
Results: The estimate for the average tetrahydrocannabinol content was 0.011%, with a 95% CI (0.004−0.019). Leave-on cosmetics products are more likely to contain total tetrahydrocannabinol compared to rinse-off cosmetics (p = 0.041). Although there was no statistically significant difference in the total tetrahydrocannabinol according to cosmetic category, there was a tendency towards higher tetrahydrocannabinol content in hand-care products, baby products, and body care preparations.
Conclusion: The current study reveals the need for producers of cannabinoid-based cosmetic products to issue quality certificates for each batch produced to inform users of the tested levels of tetrahydrocannabinol.
Keywords: tetrahydrocannabinol, over-the-counter, Cannabis sativa, cannabidiol
Introduction
References
Notes
This presentation is faithful to the original, with only a few minor changes to presentation. Some grammar and punctuation was cleaned up to improve readability. In some cases important information was missing from the references, and that information was added.
