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As seen in the previous chapters, analytical testing of cannabis is not a simple, one-size-fits-all process. Differing analytical matrices with a slightly fragmented but improving regulatory- and standards-based atmosphere, paired with downward pricing pressures and requests for quick turnaround times (TATs), means there are plenty of challenges for cannabis testing laboratories.[1][2] Workflows differ based upon the analyte being tested for and the substance in which they are contained. The sampling and anlysis of inflorescence material will look significantly different than sampling and analyzing from a cannabis edible, for example. The samples received in the lab must be tracked at every step, and results must be reported to not only clients but also state regulatory groups, typically in a secure electronic format. Quality control must be maintained, documents stored, and regulations followed. Managing all these and other aspects of the laboratory immersed in an already competitive industry leaves little room for failure. Applying automation in these cases may prove to be most beneficial.

Broadly speaking, adding elements of automation to the cannabis testing lab can help overcome the demand of rapidly analyzing large sample volumes of cannabis products with a wide spectrum of matrices.[1][2][3] Those automation elements can take many forms. Analytical lab Cannalysis, for example, has added middleware "that integrates instruments, optimizes workflows and monitors performance to create a cohesive lab ecosystem."[2] The Richland County Sheriff's Department Drug Identification Unit has turned to an automated dispersive pipette extraction (DPX) method with an automated liquid handler to speed up discriminate testing of cannabis' ∆9‐tetrahydrocannabinol (THC) content.[4] And other laboratories are turning to a LIMS for automating laboratory workflows, sample management, document management, and other aspects of cannabis lab testing.[5][6]

The LIMS has been a useful tool for laboratories since at least the 1980s, aiding with sample reception and management, test management, instrument management, and reporting.[7][8] Since its humble origins, the software has expanded to include a wide variety of additional functionality to support laboratory operations, as well as the lab's ability to adhere to standards, regulations, and accreditation requirements. The technology behind how they are deployed has even changed, with both on-site and cloud-based installations now available.

With so many vendor options, features, and requirements, the selection of a LIMS for cannabis testing can be a bewildering process, requiring significant research and consideration. Not only will you be looking for the above functionality, but you'll also want to ask other important questions. How useable and customizable is the software? Does it have sufficient mechanisms for ensuring the integrity of the data it houses and manages? How well does the vendor maintain the software with updates and patches?[9] These questions and more are required when preparing to add or change the LIMS in your laboratory, including asking the question "how flexible is this LIMS?".

References

  1. 1.0 1.1 Kaul, S. (3 June 2020). "Managing a Cannabis Lab". Lab Manager. https://www.labmanager.com/business-management/managing-a-cannabis-lab-22822. Retrieved 07 July 2021. 
  2. 2.0 2.1 2.2 Cannalysis (8 April 2020). "Cannalysis Lab Decreases Processing Time by 94% with Lab Automation Software". Analytical Cannabis. https://www.analyticalcannabis.com/articles/cannalysis-lab-decreases-processing-time-by-94-with-lab-automation-software-312343. Retrieved 07 July 2021. 
  3. Goldman, S. (January 2021). "Automation in the Cannabis and Hemp Testing Laboratories of Tomorrow". Technology Networks. Archived from the original on 19 January 2021. https://web.archive.org/web/20210119211553/https://www.technologynetworks.com/tn/webinars/automation-in-the-cannabis-hemp-testing-laboratories-of-tomorrow-344293. Retrieved 07 July 2021. 
  4. Horne, M.; Mastrianni, K.R.; Amick, G. et al. (2020). "Fast Discrimination of Marijuana using Automated High‐throughput Cannabis Sample Preparation and Analysis by Gas Chromatography–Mass Spectrometry". Journal of Forensic Sciences 65 (5): 1709–15. doi:10.1111/1556-4029.14525. 
  5. Modern Canna Labs (29 September 2020). "Importance of LIMS in Hemp Testing Laboratories". https://www.moderncanna.com/cannabis-testing/importance-of-lims-in-hemp-testing-laboratories/. Retrieved 07 July 2021. 
  6. Apte, A. (27 March 2019). "The Role of LIMS in Achieving ISO 17025 Compliance in Cannabis Testing Laboratories". LabRoots. https://www.labroots.com/webinar/role-lims-achieving-iso-17025-compliance-cannabis-testing-laboratories. Retrieved 07 July 2021. 
  7. Gibbon, G.A. (1996). "A brief history of LIMS". Laboratory Automation and Information Management 32 (1): 1–5. doi:10.1016/1381-141X(95)00024-K. 
  8. McLelland, A. (1998). "What is a LIMS - a laboratory toy, or a critical IT component?" (PDF). Royal Society of Chemistry. p. 1. Archived from the original on 04 October 2013. https://web.archive.org/web/20131004232754/http://www.rsc.org/pdf/andiv/tech.pdf. Retrieved 07 July 2021. 
  9. Kyobe, S.; Musinguzi, H.; Lwanga, N. et al. (2017). "Selecting a Laboratory Information Management System for Biorepositories in Low- and Middle-Income Countries: The H3Africa Experience and Lessons Learned". Biopreservation and Biobanking 15 (2): 112–15. doi:10.1089/bio.2017.0006.