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'''"[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF]]"'''
'''"[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF]]"'''


A method has been developed to screen [[Cannabis concentrate|cannabis extracts]] for more than 1,000 [[pesticide]]s and environmental pollutants using [[gas chromatography]] coupled to a high-resolution accurate mass [[quadrupole]] [[Time-of-flight mass spectrometry|time-of-flight mass spectrometer]] (GC/Q-TOF). An extraction procedure was developed using [[wikipedia:Acetonitrile|acetonitrile]] with [[solid-phase extraction]] cleanup. Before analysis, extracts were diluted 125:1 with [[solvent]]. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate [[Mass spectrometry|mass spectra]] for pesticides and other environmental pollutants. In the first approach, a Find-by-Fragments (FbF) software tool extracted several characteristic exact mass ions within a small retention time window where the compound [[Elution|eluted]]. ('''[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Full article...]]''')<br />
A method has been developed to screen [[Cannabis concentrate|cannabis extracts]] for more than 1,000 [[pesticide]]s and environmental pollutants using [[gas chromatography]] coupled to a high-resolution accurate mass [[quadrupole]] [[Time-of-flight mass spectrometry|time-of-flight mass spectrometer]] (GC/Q-TOF). An extraction procedure was developed using [[wikipedia:Acetonitrile|acetonitrile]] with [[solid-phase extraction]] cleanup. Before analysis, extracts were diluted 125:1 with [[solvent]]. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate [[Mass spectrometry|mass spectra]] for pesticides and other environmental pollutants. ('''[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Full article...]]''')<br />
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Revision as of 19:49, 1 December 2020

Fig6 Wylie MedCannCannab2020 3-1.jpg

"Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF"

A method has been developed to screen cannabis extracts for more than 1,000 pesticides and environmental pollutants using gas chromatography coupled to a high-resolution accurate mass quadrupole time-of-flight mass spectrometer (GC/Q-TOF). An extraction procedure was developed using acetonitrile with solid-phase extraction cleanup. Before analysis, extracts were diluted 125:1 with solvent. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate mass spectra for pesticides and other environmental pollutants. (Full article...)

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