Difference between revisions of "Template:Article of the month"

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'''"[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF]]"'''
'''"[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF]]"'''


A method has been developed to screen [[Cannabis concentrate|cannabis extracts]] for more than 1,000 [[pesticide]]s and environmental pollutants using [[gas chromatography]] coupled to a high-resolution accurate mass [[quadrupole]] [[Time-of-flight mass spectrometry|time-of-flight mass spectrometer]] (GC/Q-TOF). An extraction procedure was developed using [[wikipedia:Acetonitrile|acetonitrile]] with [[solid-phase extraction]] cleanup. Before analysis, extracts were diluted 125:1 with [[solvent]]. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate [[Mass spectrometry|mass spectra]] for pesticides and other environmental pollutants. In the first approach, a Find-by-Fragments (FbF) software tool extracted several characteristic exact mass ions within a small retention time window where the compound [[Elution|eluted]]. For each compound in the PCDL, the software evaluated the peak shape and retention time of each ion, as well as the monoisotopic exact mass, ion ratios, and other factors to decide if the compound was present or not. ('''[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Full article...]]''')<br />
A method has been developed to screen [[Cannabis concentrate|cannabis extracts]] for more than 1,000 [[pesticide]]s and environmental pollutants using [[gas chromatography]] coupled to a high-resolution accurate mass [[quadrupole]] [[Time-of-flight mass spectrometry|time-of-flight mass spectrometer]] (GC/Q-TOF). An extraction procedure was developed using [[wikipedia:Acetonitrile|acetonitrile]] with [[solid-phase extraction]] cleanup. Before analysis, extracts were diluted 125:1 with [[solvent]]. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate [[Mass spectrometry|mass spectra]] for pesticides and other environmental pollutants. In the first approach, a Find-by-Fragments (FbF) software tool extracted several characteristic exact mass ions within a small retention time window where the compound [[Elution|eluted]]. ('''[[Journal:Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF|Full article...]]''')<br />
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Revision as of 19:49, 1 December 2020

Fig6 Wylie MedCannCannab2020 3-1.jpg

"Screening for more than 1,000 pesticides and environmental contaminants in cannabis by GC/Q-TOF"

A method has been developed to screen cannabis extracts for more than 1,000 pesticides and environmental pollutants using gas chromatography coupled to a high-resolution accurate mass quadrupole time-of-flight mass spectrometer (GC/Q-TOF). An extraction procedure was developed using acetonitrile with solid-phase extraction cleanup. Before analysis, extracts were diluted 125:1 with solvent. Two data mining approaches were used together with a retention-time-locked Personal Compound Database and Library (PCDL) containing high-resolution accurate mass spectra for pesticides and other environmental pollutants. In the first approach, a Find-by-Fragments (FbF) software tool extracted several characteristic exact mass ions within a small retention time window where the compound eluted. (Full article...)

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